1. AstraZeneca’s breast cancer drug fails major trial after FDA approval

AstraZeneca’s breast cancer drug fails major trial after FDA approval

World

  • AstraZeneca’s breast cancer drug camizestrant failed to meet the main goal in a late-stage clinical trial.
  • The Phase 3 SERENA-4 trial involved 1,371 patients with previously untreated advanced breast cancer.
  • Camizestrant showed a numerical improvement in delaying cancer progression, but the result was not statistically significant.
  • The result came days after the US FDA approved the drug for a specific group with ESR1-mutated advanced breast cancer, based on another trial.

Source: ndtv.com

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